Demonstration of antibodies to Mycoplasma pneumoniae attachment protein in human sera and respiratory secretions.
نویسندگان
چکیده
Antibodies specific to the attachment protein of Mycoplasma pneumoniae were demonstrated in sera and respiratory secretions of human patients. The results indicate that the attachment protein is a major immunogen.
منابع مشابه
Location of attachment moiety on Mycoplasma pneumoniae.
Mycoplasma pneumoniae initiates infection in the human host by attachment to respiratory epithelium. The organism attaches by a specialized terminal structure. Monoclonal antibodies to an organism surface protein (P1) inhibited attachment to respiratory epithelium and were localized to the tip structure by a ferritin antibody label. The P1 protein was degraded by trypsin treatment to smaller po...
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عنوان ژورنال:
- Infection and immunity
دوره 41 1 شماره
صفحات -
تاریخ انتشار 1983